Synthesis of 4-substituted methylidene oxindoles

 

Spectroscopic Method: MS-ESI
Substituent: Chloro
MS Spectrum of (3E)-3-(4-Chlorobenzylidene)-1,3-dihydro-2H-indol-2-one:



The mass spectrum of (3E)-3-(4-Chlorobenzylidene)-1,3-dihydro-2H-indol-2-one has been obtained by positive electrospray ionization (ESI). The peak at m/e =256.2 confirms the molecular mass of this compound as the molecular ion gains a proton.

Interpretation of MS Spectrum of (3E)-3-(4-Chlorobenzylidene)-1,3-dihydro-2H-indol-2-one:

Peak Position	Diff. between molecular mass and peak	Suspected molecules or ions	Inference
258.2	258-255=3	(M+H)+ H(1)	Molecular ion gains a proton, 37Cl isotope present.
259.2	259-255=4	(M+He)+ He(4)	Compound gains helium atom
288.2	288-255=33	(M+MeOH)+ MeOH(32)	Molecular ion gains methanol, 13C isotope present.
290.2	290-255=35	(M+H2O+NH3)+ H2O(18), NH3(17)	Molecular ion gains water and ammonia molecules
299.2	299-255=44	(M+CO2)+ CO2(44)	Compound gains carbon (IV) oxide molecule.
297.2	297-255=42	(M+Na+H2O)+ Na(23), H2O(18)	Molecular ion gains water and sodium atom
273.2	273-255=18	(M+H2O)+	Compound gains water